| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00243 | Real-world experience of Faricimab (Vabysmo) treatment for macular pathology in Switzerland | personal data/biological material | monocentric | PD. Dr. med. Martin K. Schmid | Luzerner Kantonsspital |
Augenklinik Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.03.2024 | |||||||
| 2024-00242 | Exploring systemic manifestation of cutaneous T-cell lymphoma | non clinical, involving persons | monocentric | A | Dr. med. Dr. sc. med. Egle Ramelyte | University Hospital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | ||||||
| 2024-00238 | Inspiratory effort during assisted ventilation: what is normal? | personal data/biological material | multicentric | Francesca Porta | Kantonspital Graubünden |
Kantonspital Graubünden, Chur Ospedale Civico di Lugano, Lugano |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 26.03.2024 | ||||||
| 2024-00236 | Patient severity based on the NACA Score in Polytrauma: an observational retrospective study | personal data/biological material | monocentric | Prof Dr. med Christian Candrian | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 15.04.2024 | |||||||
| 2024-00230 | MK-2870-019: A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC not Achieving pCR After Receiving Neoad More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Michael Mark | Merck Sharp & Dohme LLC |
Kantonsspital Graubünden, Chur Spital Thurgau AG, Thurgau HFR hôpital fribourgeois, Fribourg |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||
| 2024-00229 | Biomechanical Evaluation of Various Refixation Techniques Following Extended Trochanteric Osteotomy and Trochanteric Fractures in a Cadaver Model | deceased persons | monocentric | Prof. Dr. med. Patrick Zingg | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2024 | |||||||
| 2024-00224 | One year results and comparison of two double mobility prostheses for trapeziometacarpal arthritis | personal data/biological material | monocentric | Sebastian Hediger | Kantonsspital Frauenfeld |
Kantonsspital Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 08.02.2024 | |||||||
| 2024-00223 |
Efficacy of Transversus Thoracic Muscle Plane Block in Patients undergoing Cardiac Surgery A randomized controlled, double blind trial |
clinical trial | other clinical trials | monocentric | A | PD Dr Sina Grape | Hôpital du Valais |
Service d'Anesthésiologie, Centre Hospitalier du Valais Romand, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||||
| 2024-00222 | Malleostapedotomy: a 20-year updated review of surgical results | personal data/biological material | monocentric | Prof. Dr. med. Thomas Linder | HNO LUKS |
HNO LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.02.2024 | |||||||
| 2024-00218 | Evaluation of the electrical and mechanical properties of the glioblastoma microenvironment and the tumor interactions with existing neural circuits | personal data/biological material | monocentric | Prof. Dr. Dr. G. Hutter | NCH Basel |
NCH Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.02.2024 | |||||||
| 2024-00216 | Processing Spoken Language and Cognition in Chronic Subjective Tinnitus | non clinical, involving persons | monocentric | A | Prof. Dr. rer. nat. Martin Meyer | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 23.04.2024 | ||||||
| 2024-00215 | CAIN457E22101 - An open-label, multicenter study to evaluate the pharmacokinetics, safety and tolerability of intravenous secukinumab infusion in adults with giant cell arteritis (GCA) or polymyalgia More ... | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Thomas Daikeler | Novartis Pharma Schweiz AG |
Universitätsspital Basel, Basel Inselspital Bern - Universitätsspital, Bern Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 04.04.2024 | |||
| 2024-00212 | Testing the Effectiveness of a Cultural-Adapted Skills-Training to Reduce Mental Health Problems in Migrants | clinical trial | other clinical trials | monocentric | A | Dr. phil. Donja Brunner | University Psychiatric Clinics Basel |
University Psychiatric Clinics Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | yes | ||||
| 2024-00210 | Seizure, Cognitive, and Functional Outcomes of Pediatric Epilepsy treated with Ketogenic Diet Therapy | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani, PhD | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||||
| 2024-00205 | Purpura de Henoch-Schönlein avec atteinte rénale : analyse des cas pédiatriques traités au CHUV | personal data/biological material | monocentric | Pr Hassib CHEHADE | CHUV - DFME |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||||||
| 2024-00204 |
SAKK 08/14 Subproject Bodycomposition Quantitative assessment of sarcopenia, osteopenia and fat distribution in patients with castration resistant prostate cancer before and during therapy with enzal More ... |
personal data/biological material | multicentric | Prof Dr Med Stefania Maria Rita Rizzo | SAKK |
Clinica di Radiologia EOC, IIMSI, Lugano Kantonsspital Aarau AG, Aarau Kantonsspital Olten, Olten Tumorzentrum Medizinische Onkologie & Palliative Care Luzerner Kantonsspital, Luzern Hôpitaux Universi More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 11.04.2024 | ||||||
| 2024-00203 | Lupus érythémateux disséminé avec néphropathie lupique : analyse des cas pédiatriques traités au CHUV | personal data/biological material | monocentric | Pr Hassib CHEHADE | CHUV - DFME |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.05.2024 | |||||||
| 2024-00202 | 68Ga-DOTA-exendin-4 PET/CT for the localization of insulinoma: An international, dual-center, retrospective, open-label real-world data study | personal data/biological material | monocentric | Dr. med. Julia Fricke | Department of Nuclear Medicine, University Hospital Basel |
Department of Nuclear Medicine University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.03.2024 | |||||||
| 2024-00200 | REGISTER FOR CLINICAL OUTCOMES BY MITEK SPORTS (MS-CORE [MITEK SPORTS CLINICAL OUTCOMES REGISTRY]) | personal data/biological material | monocentric | Dr. med. David Haeni | DePuy Synthes Products, Inc |
Altius Swiss Sportmed Center AG, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.03.2024 | |||||||
| 2024-00197 | Companion Diagnostic: Protocol for Use of VENTANA FOLR1 (FOLR1-2.1) CDx Assay in Sutro Biopharma Study STRO-002-GM3 | personal data/biological material | monocentric | Paul Mesange | Roche Tissue Diagnostic |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.03.2024 | |||||||