| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00130 |
Neurodevelopmental Outcome Registry for CHIldren with complex congenital heart Disease (ORCHID) in Switzerland – Impact of perioperative extracorporeal life support on neurodevelopmental outcome? W More ... |
personal data/biological material | multicentric | Prof. Walter Knirsch | University Children's Hospital Zurich |
University Children's Hospital, Zurich Inselspital Bern, Bern HCUGE, Geneva CHUV, Lausanne University Children's Hospital, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève More ... | 19.03.2024 | ||||||
| 2024-00128 | Prospective International multicentric evaluation of anterior midline skull base meningiomas operated through different approaches: efficacy and complication analysis | personal data/biological material | monocentric | Prof Roy Daniel | University Hospital of Brussels (UZB) |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 01.03.2024 | |||||||
| 2024-00126 | Short-term Exposure to High Altitude in Patients with Asymptomatic Aortic Stenosis | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med. Thomas Pilgrim | Insel Gruppe AG |
Insel Gruppe AG, 3010 Bern |
Kantonale Ethikkommission Bern | 30.04.2024 | |||||
| 2024-00125 | MK-2870-010: An Open-label, Randomized Phase 3 Study of MK-2870 as a Single Agent and in Combination with Pembrolizumab Versus Treatment of Physician’s Choice in Participants with HR+/HER2- Unresectab More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Urs Breitenstein | Merck Sharp & Dohme LLC |
Brust-Zentrum Zürich, Zürich Spital Thun, Thun Universitätsspital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 07.05.2024 | |||
| 2024-00122 |
European Molecular PlasmA profiling / liquid-biopsy program in THE NSCLC patients (EMPATHY NSCLC) |
non clinical, involving persons | monocentric | A | Pr Alfredo Addeo | HederaDx Switzerland |
HUG, Service d'oncologie médicale, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 29.04.2024 | ||||||
| 2024-00120 | Antioxidant-based therapies in male infertility: An observational study on sperm DNA-fragmentation and factors influencing the treatment effects | non clinical, involving persons | monocentric | A | Dr. med. Janna Pape | Women's hospital Bern |
Women's hospital Bern, Bern |
Kantonale Ethikkommission Bern | 29.04.2024 | ||||||
| 2024-00119 | Dual AntiPlatelet Therapy for PRevention of recurrent ischemic EVents in patients with rEcent acute ischemic stroke or traNsienT ischemic attack in clinical practice (DAPT PREVENT) | personal data/biological material | monocentric | Prof. Dr. Gian Marco De Marchis | Cantonal Hospital St. Gallen |
Cantonal Hospital St. Gallen, Dept. of Neurology, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 21.03.2024 | |||||||
| 2024-00118 | Plastic brain mechanisms underlying response practice | non clinical, involving persons | monocentric | A | Prof. tit. Lucas Spierer | UNIFR - Médecine |
University of Fribourg, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.03.2024 | ||||||
| 2024-00117 | Ex vivo characterization of pathomechanisms in osteoarthritis (ExPatOA) | personal data/biological material | monocentric | PD Dr Jeroen Geurts | CHUV - CLE-D04-404 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.02.2024 | |||||||
| 2024-00115 |
Stereotactic CT or MRI-adaptive radiation therapy for localized prostate cancer with obstructive genitourinary symptoms or prostate hyperplasia (X-SMILE) |
non clinical, involving persons | monocentric | A | PD Dr. med. Michael Mayinger | University Hospital Zurich |
UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2024 | ||||||
| 2024-00114 | Evaluation of Next Generation Sequencing (NGS) based pathogen diagnostic approach in native blood samples | non clinical, involving persons | monocentric | A | PD Dr. Alban Ramette | University of Bern |
University of Bern, Institute for Infectious Diseases, Bern |
Kantonale Ethikkommission Bern | 30.04.2024 | ||||||
| 2024-00110 | Prevalence of postoperative ileus and associations with perioperative complications, length of stay and cost in patients undergoing surgery | personal data/biological material | monocentric | Prof. Dr. med. Christian Fankhauser | Kantonsspital Luzern, Universität Luzern |
Luzernern Kantonsspital, Klinik für Urologie, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.03.2024 | |||||||
| 2024-00109 | ASSESSMENT OF IMMUNE PARAMETERS AND TREATMENT RESPONSE TO IMMUNOSUPPRESSIVE THERAPY IN RARE IMMUNOLOGICAL DISEASES | personal data/biological material | monocentric | Dr. med. Dr. sc. Jakob Nilsson | University Hospital Zurich |
University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 19.03.2024 | |||||||
| 2024-00108 |
Monozentrische, retrospektive Analyse neurochirurgischer Patienten mit plastisch-chirurgischen Rekonstruktionen |
personal data/biological material | monocentric | Dr. med. Mauro Vasella | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 12.03.2024 | |||||||
| 2024-00102 | Understanding patients with chronic cardiorespiratory dyspnea - “Establishment and analysis of a retro- and prospective database of patients with chronic dyspnea and suspicion of pulmonary hypertensio More ... | personal data/biological material | monocentric | PD Dr. Mona Lichtblau | Clinic of Pulmonology, University Hospital Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 22.03.2024 | |||||||
| 2024-00101 | Die Langzeit-Therapieeffekte bei Frauen mit histologisch, endoskopisch oder mittels MRI diagnostizierter Endometriose, Adenomyose und Endosalpingiose. | non clinical, involving persons | monocentric | A | Dr. med. Nicolas Samartzis |
Frauenklinik Spitäler Schaffhausen, Schaffhausen |
Kantonale Ethikkommission Zürich | 23.04.2024 | |||||||
| 2024-00100 | The value of modern multimodal imaging augmented with ARtificial intelliGence for the management of brain mETastases treated with stereotactic radiosurgery (TARGET) | personal data/biological material | monocentric | Dr. Luis Schiappacasse | CHUV - Radio-oncologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2024 | |||||||
| 2024-00096 | OptiTherm: Un Regard Rétrospectif sur l'Hypothermie Peropératoire - Étude Comparative des Effets de l'Hypothermie Modérée vs Profonde dans la Reconstruction de l'Hypoplasie de l'Arc Aortique | personal data/biological material | monocentric | Dr. Tornike Sologashvili | Département chirurgie cardio-vasculaire |
Hôpitaux universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.03.2024 | |||||||
| 2024-00095 | Supporting people involuntarily admitted to a psychiatric hospital through a brief case management intervention that promotes personal recovery and reduces the negative effects of coercion: a pilot st More ... | clinical trial | other clinical trials | monocentric | A | Dr Stéphane Morandi | Centre Hospitalier Universitaire Vaudois, CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.03.2024 | |||||
| 2024-00092 | Calculation of Antibiotic Stewardship Indicators | personal data/biological material | monocentric | Prof. Dr. med. Sarah Tschudin Sutter | University Bern |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.02.2024 | |||||||